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Home by Therapeutic Group Respiratory drugs

LUKAST GRANULES

LUKAST GRANULES
  • LUKAST GRANULES

Product Information

Composition:

Lukast 4 mg Granules : Each chewable tablet contains 4.16 mg montelukast sodium, equivalent to 4 mg of montelukast.

Mechanism of action:

The Cysteinyl leukotrines (LTC4, LTD4, and LTE4) are products of arachidonic acid metabolism and released from various cells, including mast cells and eosinophils. CysL.Ts have been correlated with the pathophysiology of asthma and allergic rhinitis. Montelukast binds with high affinity and selectivity to the CysL.T1 receptor in preference to other pharmacologically important airway receptors. Montelukast inhibits physiologic actions of LTD4 at the CysL.T1 receptor without any agonist activity.

Indications:

  • Montelukast is indicated for the prophylaxis and chronic treatment of asthma in adults and pediatric patients 12 months of age and older.
  • It is indicated for the prevention of exercise induced bronchoconstriction in patients 6 years of age and older.
  • It is indicated for the relief of symptoms of seasonal allergic rhinitis in patient 2 years of age and older and perennial allergic rhinitis in patients 6 months of age and older.

Contraindications:

Hypersensitivity to any component of this product

Dosage and administrations:

Asthma:

Montelukast should be taken once daily in the evening. The following doses are recommended:

  • For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg (oral granules).
  • For pediatric patients 12 to 23 months of age: one packet of 4-mg oral granules.

 

Allergic Rhinitis: the dose should be taken once daily (in the evening or in the morning)

The following doses for the treatment of symptoms of seasonal allergic rhinitis are recommended:

  • For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg (oral granules).

 

The following doses for the treatment of symptoms of perennial allergic rhinitis are recommended:

For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg (oral granules).

For pediatric patients 6 to 23 months of age: one packet of 4-mg oral granules.

How supplied:

Lukast 4 mg Granules: Pack of 7 or 20 or 28 sachets.

Categories: Respiratory drugs, Sachets
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LEVOZETRIN

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Lukast
LUKAST

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